Prof. Dr. Mehmet Çolakoğlu

Scientific publications

Updated:

Research is most useful when you understand both its question and its limits. Prof. Dr. Mehmet Cengiz Çolakoğlu is the first author of a 2025 study examining AMH and sperm retrieval outcomes.

What did the study investigate?

The researchers reviewed records from 72 men with idiopathic non-obstructive azoospermia at two IVF centres. They examined the relationship between preoperative AMH and other findings and sperm retrieval during micro-TESE.

What does this mean for an individual patient?

The paper reports observations in a specific group. One laboratory value cannot give you a certain surgical outcome or a personal chance of having a child. The study’s retrieval figures are not the doctor’s individual clinic success rate.

When reading the article, consider the patient group, retrospective design and need for validation in other settings. Do not use an AMH result alone to decide whether to have a procedure.

Questions for your consultation

You could ask: “Does my diagnosis resemble the study population?”, “Which findings could change my plan?” and “Would another specialist assessment be useful?”

Links on this page lead to the original publication and PubMed record. In a consultation with Prof. Dr. Mehmet Çolakoğlu, you can discuss where research fits alongside your existing findings and your IVF plans as a couple.

The publications section brings together the article title, authors, journal and original record. Authorship demonstrates a scientific contribution; it does not establish that a method is exclusive to one doctor or appropriate for every patient.

The research archive is separate from the doctor’s own publications. The existing archive contains 60 detailed study explanations and 9,436 catalogue records for 4 November 2021–4 November 2026. Catalogue inclusion does not mean a detailed assessment of every paper.

Scientific publications

2026 · Annals of Clinical and Analytical Medicine

The association of ovarian hyperstimulation syndrome in the early ovulation induction and procalcitonin in patients with polycystic ovary syndrome

In 60 patients with and without PCOS, the study examined procalcitonin and ovarian hyperstimulation syndrome. A day-five increase in those developing OHSS suggested a possible early marker, rather than an established standalone diagnostic test.

Sources and further reading

2025 · Česká gynekologie

Can anti-Müllerian hormone predict positive sperm retrieval in men with idiopathic non-obstructive azoospermia?

This retrospective study of 72 men with idiopathic non-obstructive azoospermia examined AMH as a predictor of sperm retrieval with micro-TESE. Higher AMH was associated with unsuccessful retrieval; the findings cannot guarantee an individual outcome.

Sources and further reading

2025 · Ege Tıp Dergisi

Effectiveness of foley catheter usage time in prevention of urinary fistula in laparoscopic hysterectomy

Records from 312 laparoscopic hysterectomies were reviewed for catheter duration and urinary fistula. Longer Foley use was associated with lower fistula risk; the observational design does not establish one catheter schedule for every patient.

Sources and further reading

2024 · Annals of Clinical and Analytical Medicine

Investigation of the effect of FSH/LH ratio on pregnancy success before IVF in infertile patients

In 265 IVF patients, baseline FSH/LH ratio was examined against ovarian response and pregnancy outcomes. A higher ratio was associated with a lower egg response, without a significant difference in pregnancy or live birth rates.

Sources and further reading

2024 · Mersin Üniversitesi Sağlık Bilimleri Dergisi

Agonist/antagonist kontrollü over hiperstimülasyon rejimlerinde serum ve folliküler sıvı iskemi modifiye albümin düzeyleri ve gebelik oranları ile ilişkisi

Sixty normal responders were compared across agonist and antagonist IVF protocols using serum and follicular-fluid ischaemia-modified albumin. Clinical pregnancy rates were similar; the oxidative-stress marker findings should be interpreted within their research setting.

Sources and further reading

2023 · Annals of Clinical and Analytical Medicine

Investigation of peripheral natural killer cell activity in recurrent miscarriages of unknown cause

The study investigates peripheral natural killer cell activity in unexplained recurrent miscarriage. It explores a possible immune association with pregnancy loss and should not be read as a recommendation for routine NK testing or immune treatment.

Sources and further reading

2023 · International Journal of Diabetes in Developing Countries

Role of ChREBP and SREBP-1c in gestational diabetes: two key players in glucose and lipid metabolism

ChREBP and SREBP-1c levels were compared in 50 pregnancies with gestational diabetes and 52 with normal glucose tolerance. Lower levels were found in the diabetes group, exploring biological pathways linking glucose and lipid metabolism.

Sources and further reading

2020 · Harran Üniversitesi Tıp Fakültesi Dergisi

Erken Gebelikte Kullanılan Vajinal, İntramuskuler veya Kombine Progesteronun Serum Progesteron Düzeylerine Etkisinin Karşılaştırılması

Among 64 women receiving progesterone for threatened miscarriage, vaginal, intramuscular and combined administration were compared. Combined treatment raised serum progesterone faster; this does not by itself demonstrate a higher live birth rate.

Sources and further reading

2020 · Turkish Journal of Obstetrics and Gynecology

Endometrial CD56+ natural killer cells in women with recurrent implantation failure: An immunohistochemical study

Endometrial CD56+ NK cells were compared in 25 women with recurrent implantation failure and 25 with previous live birth. Lower counts were found in the failure group; this small study did not test treatment effectiveness.

Sources and further reading

2019 · Selçuk Tıp Dergisi

IVF Sonrası Canlı Doğumla Sonuçlanan Heterotopik Gebelik; Olgu Sunumu

This case report describes simultaneous intrauterine and ectopic pregnancy after IVF. Following surgery for the ectopic pregnancy, the intrauterine pregnancy reached term; a single case does not establish a general success rate.

Sources and further reading

2016 · Şişli Etfal Hastanesi Tıp Bülteni

Genetik amniyosentez sonuçlarımız: 3721 vakanın analizi

This retrospective series reviews seven years of genetic amniocentesis, including indications and detected chromosome abnormalities. It contributes clinical data relevant to prenatal diagnosis and genetic counselling.

Sources and further reading

2015 · Gynecological Endocrinology

The evaluation of recombinant LH supplementation in patients with suboptimal response to recombinant FSH undergoing IVF treatment with GnRH agonist down-regulation

In suboptimal IVF responders, recombinant LH supplementation was compared with increasing FSH. Results favoured LH in the selected group; they do not establish that every patient benefits from routine LH supplementation.

Sources and further reading

2013 · Journal of Obstetrics and Gynaecology

Expression of cyclin A, cyclin E and p27 in normal, hyperplastic and frankly malignant endometrial samples

Cyclin A, cyclin E and p27 staining was studied in 75 normal, hyperplastic and malignant endometrial samples. Increased cyclin E and reduced p27 in cancer samples contributed to research into cell-cycle regulation.

Sources and further reading

2011 · Journal of Obstetrics and Gynaecology

Removal of intra-abdominal mislocated intrauterine devices by laparoscopy

Fifteen patients undergoing laparoscopic removal of intra-abdominally displaced IUDs were reviewed retrospectively. The series describes device locations and surgical outcomes; removal decisions require individual risk assessment.

Sources and further reading

2011 · Journal of Obstetrics and Gynaecology Research

Effect of pre-amniocentesis counseling on maternal pain and anxiety

In 240 pregnancies, counselling before amniocentesis was evaluated for anticipated and experienced pain and anxiety. The findings support the value of clear information in the procedure experience.

Sources and further reading

2011 · Journal of Obstetrics and Gynaecology Research

Balci technique for suspending vaginal vault at vaginal hysterectomy with reduced risk of vaginal vault prolapse

A new vaginal vault suspension technique at vaginal hysterectomy was compared with the conventional approach. Four-year follow-up reported less vault prolapse and greater vaginal length with the new technique.

Sources and further reading

2011 · Archives of Gynecology and Obstetrics

Management and outcomes of adnexal torsion: a 5-year experience

Surgical outcomes in 150 patients treated for adnexal torsion over five years were reviewed. Age, fertility preservation and suspicion of malignancy were discussed as important factors in selecting a surgical approach.

Sources and further reading

2011 · The Journal of Maternal-Fetal & Neonatal Medicine

Comparison of induction of labor with vaginal misoprostol plus oxytocin versus oxytocin alone in term primigravidae

In 101 first pregnancies, misoprostol followed by oxytocin was compared with oxytocin alone for labour induction. The combined approach shortened time to delivery; drug selection and safety require obstetric assessment.

Sources and further reading

2010 · Gynecologic and Obstetric Investigation

The effect of antenatal steroids on fetal lung maturation between the 34th and 36th week of pregnancy

Antenatal betamethasone was evaluated in 100 pregnancies at risk of delivery at 34–36 weeks. Fewer newborn respiratory problems occurred in the steroid group; the authors called for larger studies.

Sources and further reading

2010 · Fertility and Sterility

The efficacy of multiple-dose methotrexate treatment for unruptured tubal ectopic pregnancy and conversion rate to surgery: a study on 294 cases

Multiple-dose methotrexate and conversion to surgery were studied in 294 unruptured tubal ectopic pregnancies. Outcome was more closely related to mass size than initial beta-hCG; this historical series is not a current treatment protocol.

Sources and further reading

2010 · Gynecologic and Obstetric Investigation

Comparison of modified biophysical profile and Doppler ultrasound in predicting the perinatal outcome at or over 36 weeks of gestation

Modified biophysical profile and Doppler ultrasound were compared in 315 pregnancies at or beyond 36 weeks. Combining the assessments increased sensitivity for predicting certain perinatal outcomes.

Sources and further reading

2009 · Taiwanese Journal of Obstetrics and Gynecology

Management of ovarian cysts by laparoscopic extracorporeal approach using single ancillary trocar

A laparoscopic extracorporeal approach using one ancillary trocar was assessed in 220 selected patients with presumed benign ovarian cysts. Operating time, cyst removal and complications were reviewed to evaluate feasibility.

Sources and further reading

2009 · Acta Obstetricia et Gynecologica Scandinavica

Does tenaculum application to the cervix during intrauterine insemination affect pregnancy rates?

In 468 patients, cervical tenaculum application during IUI was examined for uterine contractions and pregnancy outcomes. More contractions and higher pregnancy rates were reported in the application group; one study does not establish routine necessity.

Sources and further reading

2009 · Gynecologic and Obstetric Investigation

Repeated in vitro fertilization failure and its relation with thrombophilia

Selected inherited thrombophilia variants were compared between women with repeated IVF failure and controls. The study found no significant association between the tested mutations and implantation failure.

Sources and further reading

2008 · Journal of Obstetrics and Gynaecology Research

Management and outcomes of adnexal masses during pregnancy: A 6-year experience

A six-year series reviewed adnexal masses requiring surgery during pregnancy. Most were benign; the results reflect a selected population at a tertiary referral centre.

Sources and further reading

2008 · Taiwanese Journal of Obstetrics and Gynecology

Comparison of single versus double intrauterine insemination

Single and double IUI were compared in a randomised study of 100 infertile patients. Pregnancy rates did not differ significantly; the authors noted the need for larger studies.

Sources and further reading

2007 · BJOG

The treatment of 65 women with imperforate hymen by a central incision and application of Foley catheter

Outcomes of central incision with Foley catheter placement were reported in 65 patients treated for imperforate hymen. The study evaluates patency of the opening and the surgical approach.

Sources and further reading

2007 · The European Journal of Contraception & Reproductive Health Care

Contraceptive efficacy and side effects of Implanon

Efficacy, side effects and reasons for removal were followed in 80 Implanon users. Changes in bleeding patterns were highlighted as an important part of counselling before insertion.

Sources and further reading

2006 · Geburtshilfe und Frauenheilkunde

Comparison of tubal transfer and transcervical uterine embryo transfer of immediate injected oocytes and 2–3 days old cultured embryos

Rapid tubal transfer after ICSI was compared with uterine embryo transfer. No improvement was demonstrated; laparoscopy and multiple-pregnancy risks led the authors to question its clinical suitability.

Sources and further reading

2004 · Archives of Gynecology and Obstetrics

Serum TNF-alpha, IL-6, lupus anticoagulant and anticardiolipin antibody in women with and without a past history of recurrent miscarriage

TNF-alpha, IL-6 and antiphospholipid markers were compared in women with and without recurrent miscarriage. An association with TNF-alpha was reported, without establishing causality or treatment effectiveness.

Sources and further reading

1996 · International Urogynecology Journal and Pelvic Floor Dysfunction

A new needle suspension procedure for genuine stress incontinence and anterior vaginal wall prolapse

A new suspension procedure for stress urinary incontinence and anterior vaginal wall prolapse is described through experience in 31 patients. It aims to support the bladder neck and vaginal wall.

Sources and further reading

1987 · The American Journal of Medicine

Commencement of normal menstrual cycles after 17 years in a patient with Sheehan’s syndrome

This case report concerns the return of normal menstrual cycles after 17 years in a patient with Sheehan’s syndrome. As the index record has no abstract, this description is limited to the subject stated in the title.

Sources and further reading

1986 · Clinical and Experimental Obstetrics & Gynecology

The effect of dehydroepiandrosterone sulfate prolactin and testosterone hormones in female fertility and hirsutism

The study investigated DHEAS, prolactin and testosterone in female infertility and hirsutism. Its historical hormone findings should not be used as current diagnostic thresholds or individual treatment advice.

Sources and further reading

2023 · Research Square

Increased pregnancy rates for recurrent implantation failure cases with embryos developed on autologous endometrial co-culture obtained in mono layer and determination of target patient group

This retrospective preprint compares endometrial co-culture with conventional culture in recurrent implantation failure. It reports favourable embryo-development findings; it is not presented as a peer-reviewed article or proof of causal superiority.

Sources and further reading

Prof. Dr. Mehmet Çolakoğlu

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Prof. Dr. Mehmet Çolakoğlu
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